Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

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Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

PURPOSE Cervical cancer caused by the human papilloma virus (HPV) continues to be the cause of yearly death among women. However, it is a curable disease when diagnosed at an early stage. Recently, several researches have reported that heat shock protein (HSP) 60, a chaperone protein of molecular weight of 60 kDa, is involved in carcinogenesis and apoptosis. In order to evaluate the prognostic ...

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The 60-kDa heat shock protein modulates allograft rejection.

Allograft rejection is a process of immune reactivity triggered by foreign transplantation antigens. We now demonstrate that the 60-kDa heat shock protein (hsp60), a molecule that is identical in the donor and the recipient, can regulate allograft immunity. In wild-type mice, hsp60 expression was greatly enhanced in allografts being rejected. By using MHC class II (Ealpha) promoter hsp60 transg...

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The production of molecular clones of Toxoplasma gondii-derived heat shock protein 70 kDa

Toxoplasmosis is a common and widespread infection in humans and many other species of warm–blooded animals. Toxoplasma gondii-derived heat shock protein 70 (Hsp70) may play an important role in the virulence of Toxoplasma gondii (T. gondii). In the present study, T. gondii Hsp70 was amplified by polymerase chain reaction (PCR) from the DNA of the T. gondiitachyzoite RH strain through the use o...

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CURRENT SCIENCE, VOL. 84, NO. 1, 10 JANUARY 2003 64 12. Viswanathan, S., Narayana, C. L., Ramesh, V., Desai, S. S. and Rangarajan, R., Proceedings of the Fluid Dynamics Symposium in honour of R. Narasimha on his 60th birthday, NAL SP 9315, July 1993, pp. 211–233. 13. Chakrabartty, S. K., Dhanalakshmi, K. and Mathur, J. S., Proceedings Third Asian CFD Conference, 7–11 December 1998, vol. 2, pp. ...

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The genus Paracoccidioides comprises species of dimorphic fungi that cause paracoccidioidomycosis (PCM), a systemic disease prevalent in Latin America. Here, we investigated whether administration of native 60-kDa heat shock protein of P. brasiliensis (nPbHsp60) or its recombinant counterpart (rPbHsp60) affected the course of experimental PCM. Mice were subcutaneously injected with nPbHsp60 or ...

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ژورنال

عنوان ژورنال: Yonsei Medical Journal

سال: 2009

ISSN: 0513-5796

DOI: 10.3349/ymj.2009.50.3.399